Skip to Content
MilliporeSigma

Skip To

917974

BocA1V2PF2

Synonym(s):

(S)-2-((S)-1-((S)-2-((S)-2-((tert-Butoxycarbonyl)amino)propanamido)-2-cyclohexylacetyl)pyrrolidine-2-carboxamido)-3-(4-fluorophenyl)propanoic acid, IAP E3 ligase lead for protein degrader research, SNIPER building block

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
100 mg
Please contact Customer Service for Availability
$749.00

About This Item

Empirical Formula (Hill Notation):
C30H43FN4O7
Molecular Weight:
590.68
MDL number:
UNSPSC Code:
41116105
NACRES:
NA.22

$749.00


Please contact Customer Service for Availability

Request a Bulk Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


ligand

BocA1V2PF2

Quality Segment

form

powder

reaction suitability

reagent type: ligand

functional group

carboxylic acid

storage temp.

2-8°C

SMILES string

C[C@H](NC(OC(C)(C)C)=O)C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(O)=O)CC2=CC=C(C=C2)F)=O)=O)C3CCCCC3)=O

InChI

1S/C30H43FN4O7/c1-18(32-29(41)42-30(2,3)4)25(36)34-24(20-9-6-5-7-10-20)27(38)35-16-8-11-23(35)26(37)33-22(28(39)40)17-19-12-14-21(31)15-13-19/h12-15,18,20,22-24H,5-11,16-17H2,1-4H3,(H,32,41)(H,33,37)(H,34,36)(H,39,40)/t18-,22-,23-,24-/m0/s1

InChI key

LNJCHGKSSPMNRM-IMNFJDCFSA-N

Application

BocA1V2PF2 is an in silico-derived inhibitor of apoptosis protein (IAP)-recruiting ligand for targeted protein degradation and SNIPER (specific and non-genetic IAP-dependent protein erasers) development, launched in partnership with ComInnex. Learn more about the novel IAP ligands generated through virtual screening of AVP mimetics in our Technology Spotlights. A C-terminal variant of BocA1V2PF2 is also available as A1V2PF2-NHEt (916714).

BocA1V2PF2 conjugates are also available for degrader synthesis. Browse our full synthesis offering here for streamlining
SNIPER and PROTAC® degrader libraries: Degrader Building Blocks

917443BocA1V2PF2-NHC6-NH2
917699 BocA1V2PF2-NHC10-NH2
917958 BocA1V2PF2-NHPEG1-NH2
916692 BocA1V2PF2-NHPEG3-NH2

Legal Information

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
916978917478917443
functional group

carboxylic acid

functional group

carboxylic acid

functional group

carboxylic acid

functional group

amine

reaction suitability

reagent type: ligand

reaction suitability

reagent type: ligand

reaction suitability

reagent type: ligand

reaction suitability

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

form

powder

form

powder

form

powder

form

powder

ligand

BocA1V2PF2

ligand

BocA1V2PF1

ligand

BocA1V1PF2

ligand

BocA1V2PF2


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Questions

Reviews

No rating value

Active Filters