917931
A1V2PF2-NHEt-C6-NH2
Synonym(s):
(S)-1-((S)-2-((S)-2-((6-Aminohexyl)amino)propanamido)-2-cyclohexylacetyl)-N-((S)-1-(ethylamino)-3-(4-fluorophenyl)-1-oxopropan-2-yl)pyrrolidine-2-carboxamide, AVP conjugate for IAP-mediated protein degrader development, SNIPER building block
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
50 mg | Please contact Customer Service for Availability | $659.00 |
About This Item
ligand
A1V2PF2
Quality Segment
form
powder
reaction suitability
reactivity: carboxyl reactive, reagent type: ligand-linker conjugate
functional group
amine
storage temp.
2-8°C
SMILES string
C[C@H](NCCCCCCN)C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(NCC)=O)CC2=CC=C(C=C2)F)=O)=O)C3CCCCC3)=O
InChI
1S/C33H53FN6O4/c1-3-36-31(42)27(22-24-15-17-26(34)18-16-24)38-32(43)28-14-11-21-40(28)33(44)29(25-12-7-6-8-13-25)39-30(41)23(2)37-20-10-5-4-9-19-35/h15-18,23,25,27-29,37H,3-14,19-22,35H2,1-2H3,(H,36,42)(H,38,43)(H,39,41)/t23-,27-,28-,29-/m0/s1
InChI key
MIQCHNDVWYGFFD-HPEBZSCQSA-N
Application
Building blocks in this series:
916714 A1V2PF2-NHEt
917931 A1V2PF2-NHEt-C6-NH2
916684 A1V2PF2-NHEt-C10-NH2
916935 A1V2PF2-NHEt-PEG1-NH2
917192 A1V2PF2-NHEt-PEG3-NH2
Technology Spotlight: Degrader Building Blocks with Inhibitor of Apoptosis Protein (IAP) In Silico-Derived Ligands
Other Notes
Legal Information
1 of 1
This Item | |||
|---|---|---|---|
| functional group amine | functional group amine | functional group amine | functional group amine |
| reaction suitability reactivity: carboxyl reactive, reagent type: ligand-linker conjugate | reaction suitability reactivity: carboxyl reactive, reagent type: ligand-linker conjugate | reaction suitability reactivity: carboxyl reactive, reagent type: ligand-linker conjugate | reaction suitability reactivity: carboxyl reactive, reagent type: ligand-linker conjugate |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| form powder | form powder | form powder | form powder |
| ligand A1V2PF2 | ligand A1V2PF2 | ligand A1V2PF1 | ligand A1V2PF1 |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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