Skip to Content
MilliporeSigma

Skip To

914223

Biotin-SLF

Synonym(s):

(R)-3-(3,4-Dimethoxyphenyl)-1-(3-(4,18-dioxo-22-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-8,11,14-trioxa-5,17-diazadocosanamido)phenyl)propyl (S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate, Bio-SLF, Biotin-conjugated FKBP12WT-directed ligand, Biotin-conjugated SLF ligand, FKBP12WT affinity probe for PROTAC® and targeted protein degradation research

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
5 mg
Check Cart for Availability
$743.00

About This Item

Empirical Formula (Hill Notation):
C52H76N6O13S
CAS Number:
Molecular Weight:
1025.26
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.22

$743.00


Check Cart for Availability

​
Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


ligand

biotin

Quality Segment

form

powder

storage temp.

−20°C

SMILES string

O=C(CCC(NCCOCCOCCOCCNC(CCCC[C@@H]1SC[C@@](N2)([H])[C@]1([H])NC2=O)=O)=O)NC3=CC([C@H](OC([C@@H]4CCCCN4C(C(C(C)(C)CC)=O)=O)=O)CCC5=CC=C(OC)C(OC)=C5)=CC=C3

InChI key

QFIMAWUXIBINCP-SLBVAARVSA-N

Application

Biotin-SLF (bio-SLF) is an FKBP12WT affinity probe useful in chemical biology or targeted protein degradation where FKBP12 is used as a tool protein and its enrichment is required in discovery experiments or assay validation.


Related tools:
Additional bifunctional tools for FKPB12 variants:

  • dTAG-13 (SML2601) for FKBP12F36V; and KB02-SLF (914738), KB03-SLF (914975), and KB04-SLF (913715) for FKBP12WT
  • Cereblon (CRBN) affinity probe: Biotin-Thalidomide (913979)
Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)

Legal Information

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
913715914975913669
description

-

description

-

description

≥95%

description

-

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

ligand

biotin

ligand

electrophilic fragment

ligand

electrophilic fragment

ligand

-


Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Questions

Reviews

No rating value

Active Filters