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359270

Sodium tert-butoxide

97%

Synonym(s):

Sodium 2-methylpropan-2-olate, Sodium t-butoxide, Sodium tert-butanolate, Sodium tert-butylate

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Size/SKUAvailabilityPrice
5 g
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$35.20
25 g
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$60.50
100 g
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$105.00
500 g
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$405.00
$303.75
1.5 kg
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$723.00

About This Item

Linear Formula:
NaOC(CH3)3
CAS Number:
Molecular Weight:
96.10
UNSPSC Code:
12352107
NACRES:
NA.22
PubChem Substance ID:
EC Number:
212-741-9
Beilstein/REAXYS Number:
3654215
MDL number:
Assay:
97%
Form:
powder, crystals or chunks

$35.20


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vapor pressure

0.0000026 hPa ( 50 °C)

Quality Segment

assay

97%

form

powder, crystals or chunks

density

1,025 g/cm3 at 20 °C

SMILES string

[Na+].CC(C)(C)[O-]

InChI

1S/C4H9O.Na/c1-4(2,3)5;/h1-3H3;/q-1;+1

InChI key

MFRIHAYPQRLWNB-UHFFFAOYSA-N

Application

Sodium tert-butoxide may be used as a safe and effective alternative to sodium hydride for the coupling of hydroxyethyl adenine with diethyl p-toluenesulfonyloxymethanephosphonate to form 9-[2-(diethylphosphonomethoxy)ethyl]adenine (diethyl-PMEA), which is a key intermediate to prepare adefovir dipivoxil.
It can also be used:
  • To facilitate the coupling of aryl halides with benzene derivatives in the presence of 10-phenanthroline derivative.
  • To activate first-row transition-metal pre-catalysts.
  • As a base for the amination of aryl chlorides in the presence of a novel palladacyclic precatalyst.


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This Item
703788752096359300
assay

97%

assay

99.9%

assay

-

assay

90%

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

form

powder, crystals or chunks

form

powder

form

liquid

form

crystalline powder, powder, crystals or chunks

vapor pressure

0.0000026 hPa ( 50 °C)

vapor pressure

-

vapor pressure

-

vapor pressure

-

density

1,025 g/cm3 at 20 °C

density

1.025  g/cm3 at 68 °F

density

0.918 g/mL at 25 °C

density

-


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pictograms

FlameCorrosion

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 1 - Skin Corr. 1B

supp_hazards

Storage Class

4.2 - Pyrophoric and self-heating hazardous materials

wgk

WGK 1

flash_point_f

57.2 °F

flash_point_c

14 °C

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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