This webinar explores Nanofitins®, first offering therapeutic potential across diverse indications, including cancer, respiratory, and CNS conditions independently or in combination with other modalities to create multispecific molecules or enable targeted cargo delivery. Their high stability supports alternative administration routes like oral and pulmonary delivery. Second, Nanofitins® facilitates single-step purification of targets like proteins, adeno-associated viruses (AAVs), and exosomes. Case studies covering AAVs purification show case that this customizable affinity technology, known as "Eshmuno® Fit Services" provides a scalable platform for producing next-generation biopharmaceuticals.
In this webinar, you will learn:
- Techniques for engineering proteins with high specificity, stability, and low toxicity
- The role of Nanofitins® in pharmaceutical applications
- Utilizing Nanofitins® for custom affinity chromatography
- How our custom affinity resin development services work
Speakers
Mathieu Cinier
Affilogic
CTO
Affilogic is a privately-owned biotech company specialized in discovery and development of a novel class of affinity proteins called Nanofitins. Mathieu Cinier, Ph.D., who joined the company in November 2011, brings extensive expertise in protein engineering and early drug development. He has a proven track record in leading R&D teams and managing operational activities, with a history of successfully driving Nanofitin generation programs (100+) in collaboration with industrial partners while sustaining internal R&D efforts.
Vanessa Kohl
MilliporeSigma
Scientist
Vanessa Kohl has a M.Sc. in biomolecular engineering and works as technical project lead for novel Nanofitins® affinity ligand-based chromatography materials. She started her work at MilliporeSigma in 2018 and is well experienced in protein USP and DSP. She took over several project leads for targeting recombinant proteins as well as novel modalities target purification such as adeno-associated viruses.
Carolin Golibrzuch
MilliporeSigma
Scientist
Carolin Golibrzuch has an M.Sc. in biochemistry/analytical chemistry and works as technical project lead for novel Nanofitins® affinity ligand-based chromatography materials. She started her work at MilliporeSigma in 2018 and worked in solving several analytical challenges as well as project leads for targeting recombinant protein as well as novel modalities target purification such as exosomes or AAVs.
Johannes Bueber
MilliporeSigma
Project Manager
Johannes Bueber is a project manager, operational product manager & single point of contact for Eshmuno® Fit projects. Johannes holds a Ph.D. in organic chemistry and brings in 19 years of experience in customer projects.
Pharma and biopharma manufacturing
- Pharma and biopharma manufacturing
Duration:1h
Language:English
Session 1:Thu, February 6, 2025 4:00 PM CEST
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