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I7013

Sigma-Aldrich

Imidazole-4-acetic acid sodium salt

Synonym(s):

I4AA

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About This Item

Empirical Formula (Hill Notation):
C5H5N2NaO2
CAS Number:
56368-58-2
Molecular Weight:
148.10
MDL number:
MFCD00005204
UNSPSC Code:
12352200
PubChem Substance ID:
24896104

storage temp.

2-8°C

SMILES string

[Na+].[O-]C(=O)Cc1c[nH]cn1

InChI

1S/C5H6N2O2.Na/c8-5(9)1-4-2-6-3-7-4;/h2-3H,1H2,(H,6,7)(H,8,9);/q;+1/p-1

InChI key

JDDRCOTZMQIPOQ-UHFFFAOYSA-M

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Biochem/physiol Actions

Competitive antagonist at GABAC receptors.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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A Kammeyer et al.
Biochimica et biophysica acta, 1526(3), 277-285 (2001-06-19)
cis-Urocanic acid (cis-UCA), formed from trans-urocanic acid (trans-UCA) by photoisomerization, has been shown to mimic suppressive effects of UV on the immune system. It is our hypothesis that UCA oxidation products in the skin play a role in the process
Jane E Carland et al.
The Journal of biological chemistry, 279(52), 54153-54160 (2004-10-16)
The ability of members of the nicotinicoid superfamily of ligand-gated ion channels to selectively conduct anions or cations is critical to their function within the central nervous system. Recent work has demonstrated that residues at the intracellular end of the
Yuya Oaki et al.
Nanoscale, 2(11), 2362-2365 (2010-09-14)
The organization of an imidazolium salt in the interlayer space of a layered inorganic compound leads to the formation of nanosegregated composites.
Zihao Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(37), 13793-13798 (2008-09-10)
Protein GlcNAcylation serves as a nutrient/stress sensor to modulate the functions of many nuclear and cytoplasmic proteins. O-GlcNAc cycles on serine or threonine residues like phosphorylation, is nearly as abundant, and functions, at least partially, via its interplay with phosphorylation.
Greg T Cantin et al.
Analytical chemistry, 79(12), 4666-4673 (2007-05-26)
An automated online multidimensional liquid chromatography system coupled to ESI-based tandem mass spectrometry was used to assess the effectiveness of TiO2 in the enrichment of phosphopeptides from tryptic digests of protein mixtures. By monitoring the enrichment of phosphopeptides, an optimized
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