F7307

Fotemustine

≥98% (HPLC)

• Synonym(s): (+-)-Diethyl (1-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)phosphonate, Muphoran, Mustophorane, P-[1-[[[(2-Chloroethyl)nitrosoamino]carbonyl]amino]ethyl]-phosphonic acid diethyl ester, S 10036
• Empirical Formula (Hill Notation): C₉H₁₉ClN₃O₅P
• CAS Number: 92118-27-9
• Molecular Weight: 315.69
• UNSPSC Code: 12352200
• PubChem Substance ID: 329799764
• MDL number: MFCD00866278
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: protect from light

Properties

• assay: ≥98% (HPLC)
• form: powder
• storage condition: protect from light
• color: light yellow
• solubility: H₂O: ≥1 mg/mL
• originator: Servier
• storage temp.: 2-8°C
• SMILES string: CCOP(=O)(OCC)C(C)NC(=O)N(CCCl)N=O
• InChI: 1S/C9H19ClN3O5P/c1-4-17-19(16,18-5-2)8(3)11-9(14)13(12-15)7-6-10/h8H,4-7H2,1-3H3,(H,11,14)
• InChI key: YAKWPXVTIGTRJH-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Fotemustine is a third generation nitrosourea, chloroethylating agent used in the treatment of glioma and malignant melanoma.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Servier. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• pictograms: GHS08
• signalword: Warning
• hcodes: H351
• pcodes: P281
• Hazard Classifications: Carc. 2
• Storage Class: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable