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43608

3,3′-Dipropylthiadicarbocyanine iodide

suitable for fluorescence, ≥98.0% (TLC)

Synonym(s):

3-Propyl-2-[5-[3-propyl-2(3H)-benzothiazolylidene]-1,3-pentadienyl]benzothiazolium iodide, DiSC3(5)

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100 MG

$534.00

$534.00

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About This Item

Empirical Formula (Hill Notation):
C25H27IN2S2
CAS Number:
53213-94-8
Molecular Weight:
546.53
NACRES:
NA.32
PubChem Substance ID:
57650184
UNSPSC Code:
12352116
MDL number:
MFCD00075033

Key Documents

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Quality Level

100

assay

≥98.0% (TLC)

form

powder

mp

245 °C (dec.) (lit.)

solubility

DMF: soluble

fluorescence

λex 500 nm; λem 705 nm in DMF

suitability

suitable for fluorescence

SMILES string

[I-].CCCN1C(\Sc2ccccc12)=C\C=C\C=C\c3sc4ccccc4[n+]3CCC

InChI

1S/C25H27N2S2.HI/c1-3-18-26-20-12-8-10-14-22(20)28-24(26)16-6-5-7-17-25-27(19-4-2)21-13-9-11-15-23(21)29-25;/h5-17H,3-4,18-19H2,1-2H3;1H/q+1;/p-1

InChI key

GDEURKKLNUGTDA-UHFFFAOYSA-M

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This Item
381306173754M047080
3,3′-Dipropylthiadicarbocyanine iodide suitable for fluorescence, ≥98.0% (TLC)

Sigma-Aldrich

43608

3,3′-Dipropylthiadicarbocyanine iodide

3,3′-Diethylthiatricarbocyanine iodide 99%

Sigma-Aldrich

381306

3,3′-Diethylthiatricarbocyanine iodide

3,3′-Diethylthiadicarbocyanine iodide Dye content 98 %

Sigma-Aldrich

173754

3,3′-Diethylthiadicarbocyanine iodide

Cyanine 3 Phosphoramidite configured for PerkinElmer, configured for Polygen

Sigma-Aldrich

M047080

Cyanine 3 Phosphoramidite

suitability

suitable for fluorescence

suitability

-

suitability

-

suitability

-

fluorescence

λex 500 nm; λem 705 nm in DMF

fluorescence

-

fluorescence

-

fluorescence

-

form

powder

form

-

form

-

form

-

solubility

DMF: soluble

solubility

-

solubility

-

solubility

-

assay

≥98.0% (TLC)

assay

99%

assay

-

assay

≥90% (31P-NMR), ≥95.0% (@549nm, reversed phase HPLC)

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

200

Application

3,3′-Dipropylthiadicarbocyanine iodide [DiSC3(5)] is used as a fluorogenic probe to detect and measure changes in transmembrane potential or configuration induced by membrane altering agents.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Transmembrane potential measurements[1]

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM6510
BCCK8898
BCCH6675
BCCG3331
BCCD6948

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Min Kyoung Shin et al.
Antibiotics (Basel, Switzerland), 9(7) (2020-07-28)
The prevalence of antibiotic-resistant bacteria has become an immediate threat to public health. Antimicrobial peptides are attracting attention as a new source of antibiotics due to their ability to prevent drug-resistances with fewer side effects. Spider venom is composed of
M Síp et al.
Journal of photochemistry and photobiology. B, Biology, 4(3), 321-328 (1990-01-01)
The mechanism of carbocyanine dye diS-C3-(5) fluorescence intensity variations with transmembrane potential changes has been studied using time-resolved fluorescence spectroscopy. Clear evidence is given of the transmembrane-potential-dependent partition of the dye among various sites with different fluorescence lifetimes. It was
Sonya E Neal et al.
Molecular biology of the cell, 28(21), 2773-2785 (2017-08-18)
Prokaryotes have aerobic and anaerobic electron acceptors for oxidative folding of periplasmic proteins. The mitochondrial intermembrane space has an analogous pathway with the oxidoreductase Mia40 and sulfhydryl oxidase Erv1, termed the mitochondrial intermembrane space assembly (MIA) pathway. The aerobic electron
Wen Ma et al.
Journal of proteomics, 150, 242-251 (2016-10-25)
Daptomycin (DAP) is a novel lipopeptide antibiotic which exhibits excellent antibacterial activity against most clinically relevant Gram-positive bacteria, but the DAP-targeting protein molecules against host bacterial infection are far from clear. In order to discover bacterial protein response to DAP
Venkateswarlu Yarlagadda et al.
Scientific reports, 10(1), 8134-8134 (2020-05-20)
Despite the remarkable advances due to the discovery and development of antimicrobials agents, infectious diseases remain the second leading cause of death worldwide. This fact underlines the importance of developing new therapeutic strategies to address the widespread antibiotic resistance, which
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Global Trade Item Number

SKUGTIN
43608-100MG04061833277195

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