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06922

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Hexacosanoic acid

analytical standard

Synonym(s):

Cerotic acid, Cerotinic acid

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About This Item

Linear Formula:
CH3(CH2)24COOH
CAS Number:
Molecular Weight:
396.69
Beilstein/REAXYS Number:
1799681
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

assay

≥95.0% (GC)

form

powder or crystals

shelf life

limited shelf life, expiry date on the label

format

neat

functional group

carboxylic acid

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCCCCCCCCCCCCCCC(O)=O

InChI

1S/C26H52O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26(27)28/h2-25H2,1H3,(H,27,28)

InChI key

XMHIUKTWLZUKEX-UHFFFAOYSA-N

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General description

Hexacosanoic acid is classified under the very long chain fatty acids (VLCFAs) group of biologically important compounds.

Application

Hexacosanoic acid may be used as a reference standard for the determination of hexacosanoic acid
  • in human serum and plasma samples for the screening of peroxisomal disorders by gas chromatography-mass spectrometry (GC-MS) operating under selected-ion monitoring (SIM) mode
  • in biological samples by GC-MS
  • in microalgal lipids by solid-phase extraction (SPE) followed by GC-MS analysis
  • as a naphthoxyethyl derivative by high performance liquid chromatography (HPLC) coupled with fluorometric detection

Analysis Note

LC-MS: identity conformes

Storage Class

11 - Combustible Solids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Separation of triacylglycerols and free fatty acids in microalgal lipids by solid-phase extraction for separate fatty acid profiling analysis by gas chromatography.
Paik MJ, et al.
Journal of Chromatography A, 1216(31), 5917-5923 (2009)
Gas chromatography/mass spectrometry analysis of very long chain fatty acids, docosahexaenoic acid, phytanic acid and plasmalogen for the screening of peroxisomal disorders.
Takemoto Y, et al.
Brain & Development, 25(7), 481-487 (2003)
A fluorimetric liquid chromatography for highly sensitive analysis of very long chain fatty acids as naphthoxyethyl derivatives.
Lu CY, et al.
Chromatographia, 51(5-6), 315-321 (2000)
High sensitivity quantitative lipidomics analysis of fatty acids in biological samples by gas chromatography-mass spectrometry.
Quehenberger O, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1811(11), 648-656 (2011)
Nicol Kruska et al.
Biochimica et biophysica acta, 1852(5), 925-936 (2015-01-15)
X-linked adrenoleukodystrophy (X-ALD) is a severe neurodegenerative disorder resulting from defective ABCD1 transport protein. ABCD1 mediates peroxisomal uptake of free very-long-chain fatty acids (VLCFA) as well as their CoA-esters. Consequently, VLCFA accumulate in patients' plasma and tissues, which is considered

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