IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor, leading to the activation of MAP kinases and NF-kappaB. IL-33 induces production of helper T-cell type 2 (TH2) cytokines, including IL-4, IL-5 and IL-13, and is a known mediator of many inflammation responses. Cat. No. ABF108, Anti-IL-33, is an affinity purified rabbit polyclonal antibody that recognizes epitopes in the C-terminal half of murine IL-33. Reactivity to rat or other species has not been tested.
Immunogen
Epitope: C-Terminal
His-tagged recombinant protein corresponding to the C-Terminal of mouse IL-33.
Application
Anti-IL-33 Antibody is an antibody against IL-33 for use in Western Blotting, Flow Cytometry.
Flow Cytometry Analysis: 0.25 µg of this antibody from a representative lot detected IL-33 in 1X10E6 monensin treated MEF1 cells.
Research Category Inflammation & Immunology
Research Sub Category Immunoglobulins & Immunology
Quality
Evaluated by Western Blotting in MEF1 cell lysate.
Western Blotting Analysis: 0.1 µg/mL of this antibody detected IL-33 in 10 µg of MEF1 cell lysate.
Target description
~35 kDa observed. Uncharacterized band(s) may appear in some lysates.
Physical form
Affinity
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Other Notes
Concentration: Please refer to lot specific datasheet.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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