C69128

3-Chloropropionyl chloride

98%

• Synonym(s): (Chloromethyl)acetyl chloride, 3-Chloropropionic acid chloride
• Linear Formula: ClCH₂CH₂COCl
• CAS Number: 625-36-5
• Molecular Weight: 126.97
• Beilstein/REAXYS Number: 635814
• EC Number: 210-890-4
• MDL number: MFCD00000747
• UNSPSC Code: 12352100
• PubChem Substance ID: 24892912
• NACRES: NA.22

Properties

• assay: 98%
• form: liquid
• refractive index: n20/D 1.457 (lit.)
• bp: 143-145 °C (lit.)
• density: 1.33 g/mL at 25 °C (lit.)
• SMILES string: ClCCC(Cl)=O
• InChI: 1S/C3H4Cl2O/c4-2-1-3(5)6/h1-2H2
• InChI key: INUNLMUAPJVRME-UHFFFAOYSA-N

Description

Application

• Microwave-enhanced liquid-phase synthesis of thiohydantoins and thioxotetrahydropyrimidinones.: This study explores the use of microwave-enhanced synthesis methods for producing thiohydantoins and thioxotetrahydropyrimidinones, with 3-Chloropropionyl chloride as a key reagent. The results indicate that microwave irradiation significantly accelerates the reaction times and enhances the yields, making this a valuable technique for organic synthesis applications (Yeh et al., 2003).
• Diethylaminopropionamido-hydroxy-anthraquinones as potential anticancer agents: synthesis and characterization.: This paper discusses the synthesis of novel anthraquinone derivatives using 3-Chloropropionyl chloride. These compounds have shown potential as anticancer agents, demonstrating significant biological activity in preliminary tests. The study provides detailed characterization of the synthesized compounds and their potential therapeutic applications (Antonello et al., 1989).

Safety Information

• pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H290,H302,H314,H330
• pcodes: P234 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A
• supp_hazards: EUH014
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 1
• flash_point_f: 158.9 °F - closed cup
• flash_point_c: 70.5 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter