A4056

Amrinone

• Synonym(s): 5-Amino-(3,4′-bipyridin)-6(1H)-one, Inamrinone
• Empirical Formula (Hill Notation): C₁₀H₉N₃O
• CAS Number: 60719-84-8
• Molecular Weight: 187.20
• UNSPSC Code: 12352202
• PubChem Substance ID: 24890741
• EC Number: 262-390-0
• MDL number: MFCD00083228

Properties

• assay: ≥98% (TLC)
• Quality Segment: 200
• form: powder
• solubility: 1 M NaOH: 100 mg/mL
• storage temp.: 2-8°C
• SMILES string: NC1=CC(=CNC1=O)c2ccncc2
• InChI: 1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14)
• InChI key: RNLQIBCLLYYYFJ-UHFFFAOYSA-N
• Gene Information: human ... PDE3A(5139) ; rat ... Pde3a(50678)

Description

Biochem/physiol Actions

Simple, non-glycoside cardiotonic agent, possibly via its phosphodiesterase III (PDE-III) inhibitory action.

Simple, non-glycoside cardiotonic agent, possibly via its phosphodiesterase III (PDE-III) inhibitory action. Independent of its cardiac effects, amrinone provides protection against ischemia-reperfusion injury in kidney, liver, and heart.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Codes: H301
• Precautionary Statements: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges