Skip to Content
MilliporeSigma
All Photos(1)

Documents

M0513

Supelco

Megestrol acetate

analytical standard, for drug analysis

Synonym(s):

17α-Acetoxy-6-methyl-4,6-pregnadiene-3,20-dione, 17α-Hydroxy-6-methyl-4,6-pregnadiene-3,20-dione 17-acetate, 17α-Hydroxy-6-methyl-6-dehydroprogesterone 17-acetate, Megestrol 17-acetate

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C24H32O4
CAS Number:
Molecular Weight:
384.51
Beilstein/REAXYS Number:
1917291
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard, for drug analysis

Quality Level

assay

≥99% (HPLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

format

neat

SMILES string

[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@]3(OC(C)=O)C(C)=O)[C@]1([H])C=C(C)C4=CC(=O)CC[C@]24C

InChI

1S/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h12-13,18-20H,6-11H2,1-5H3/t18-,19+,20+,22-,23+,24+/m1/s1

InChI key

RQZAXGRLVPAYTJ-GQFGMJRRSA-N

Gene Information

human ... PGR(5241)

Looking for similar products? Visit Product Comparison Guide

General description

Megestrol acetate is a commonly used synthetically prepared glucosteroid, which possesses anti-inflammatory property.

Application

Megestrol acetate may be used as a reference standard for the determination of megestrol acetate in human serum using reversed-phase high performance liquid chromatography (RP-HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Determination of megestrol acetate and cyproterone acetate in serum of patients with advanced breast cancer by high-performance liquid chromatography
Dikkeschei.D.L, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 529, 145-154 (1990)
Handbook of Clinical Nutrition and Aging (2009)
Yo Han Kim et al.
Clinical therapeutics, 37(2), 439-447 (2014-12-03)
Megestrol acetate oral suspension is an appetite stimulant indicated for cachexia. It is available in a conventional formulation and as a nanocrystal dispersion. The aim of this study was to compare the tolerability and pharmacokinetics of these formulations under fed
Navdha Mittal et al.
PloS one, 9(10), e110410-e110410 (2014-10-24)
Resistance to progestin treatment is a major hurdle in the treatment of advanced and reoccurring endometrial cancer. Fenretinide is a synthetic retinoid that has been evaluated in clinical trials as a cancer therapeutic and chemo-preventive agent. Fenretinide has been established
Francisco J Prado-Prado et al.
Bioorganic & medicinal chemistry, 18(6), 2225-2231 (2010-02-27)
There are many of pathogen parasite species with different susceptibility profile to antiparasitic drugs. Unfortunately, almost QSAR models predict the biological activity of drugs against only one parasite species. Consequently, predicting the probability with which a drug is active against

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service