A8251

Acriflavine hydrochloride

Powder

• Synonym(s): 3,6-Diamino-10-methylacridinium chloride hydrochloride, Euflavine
• CAS Number: 8063-24-9
• NACRES: NA.47
• PubChem Substance ID: 24891216
• UNSPSC Code: 12171500
• MDL number: MFCD00069039
• Beilstein/REAXYS Number: 6265525

Properties

• Product Name: Acriflavine hydrochloride, fluorescent dye
• Quality Segment: 200
• form: powder
• composition: Acriflavine HCL content, 10-50% , Proflavine HCL, 25-70%
• technique(s): microbe id | staining: suitable
• color: faint brown to brown, and Orange to Dark Orange and Red to Very Dark Red
• mp: 260 °C (dec.) (lit.)
• solubility: H₂O: 1 mg/mL
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: [Cl-].Cl[H].Cl[H].Nc1ccc2cc3ccc(N)cc3nc2c1.C[n+]4c5cc(N)ccc5cc6ccc(N)cc46
• InChI: 1S/C14H13N3.C13H11N3.3ClH/c1-17-13-7-11(15)4-2-9(13)6-10-3-5-12(16)8-14(10)17;14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;;;/h2-8H,1H3,(H3,15,16);1-7H,14-15H2;3*1H
• InChI key: MKLTXAHQKDVBLY-UHFFFAOYSA-N

Description

Application

In living mice, acriflavine hydrochloride has been used in the confocal laser endomicroscopy to check the crypt structure in mucosa. It has also been used in Neurospora strain selection by checking the acriflavine resistance.

Biochem/physiol Actions

Acriflavine hydrochloride is a fluorescent dye. It is used as a topical contrast agent. It mainly stains nuclei and is applied to tissues before microscopy.

Other Notes

A mixture of 3,6-diamino-10-methylacridinium (acriflavin) and 3,6-diaminoacridine (proflavin)

Safety Information

• pictograms: GHS05,GHS07,GHS09
• signalword: Danger
• hcodes: H302,H318,H411
• pcodes: P264 - P273 - P280 - P301 + P312 - P305 + P351 + P338 - P391
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1
• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves