31737

Sulfamethoxazole

VETRANAL^®, analytical standard

• Synonym(s): 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide, N¹-(5-Methylisoxazol-3-yl)sulfanilamide
• Empirical Formula (Hill Notation): C₁₀H₁₁N₃O₃S
• CAS Number: 723-46-6
• Molecular Weight: 253.28
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329753910
• EC Number: 211-963-3
• Beilstein/REAXYS Number: 6732984
• MDL number: MFCD00010546

Properties

• grade: analytical standard
• Quality Segment: 100
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• SMILES string: Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
• InChI: 1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
• InChI key: JLKIGFTWXXRPMT-UHFFFAOYSA-N

Description

General description

Sulfamethoxazole is a bacteriostatic antibiotic used in treating coccidiosis, diarrhea and gastroenteritis in humans and is also a known veterinary drug. Sulfamethoxazole in combination with trimethoprim is effective in treating pneumonia. Sulfamethoxazole acts by blocking the folic acid metabolism to produce synergistic antibacterial activity.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Sulfamethoxazole may be used as a reference standard for the determination of the analyte in:

• Bovine milk by high-performance liquid chromatography method.
• Pharmaceutical formulations and biological samples by capillary electrophoresis (CE) with end-column electrochemical detection (EC).

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS08,GHS09
• signalword: Warning
• hcodes: H361fd,H411
• pcodes: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Hazard Classifications: Aquatic Chronic 2 - Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves