11546

3′-Azido-3′-deoxythymidine

≥99.0% (HPLC)

• Synonym(s): AZT, Azidothymidine, ZDV, Zidovudine
• Empirical Formula (Hill Notation): C₁₀H₁₃N₅O₄
• CAS Number: 30516-87-1
• Molecular Weight: 267.24
• PubChem Substance ID: 329749478
• UNSPSC Code: 12352200
• Beilstein/REAXYS Number: 3595791
• MDL number: MFCD00006536

Properties

• biological source: synthetic
• assay: ≥99.0% (HPLC)
• form: powder with small lumps
• impurities: ≤0.5% water
• mp: 113-115 °C (lit.)
• solubility: H₂O: 50 mg/mL, clear, colorless to slightly yellow
• storage temp.: −20°C
• SMILES string: CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
• InChI: 1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
• InChI key: HBOMLICNUCNMMY-XLPZGREQSA-N

Description

Biochem/physiol Actions

Reverse transcriptase inhibitor active against HIV-1 virus.

Other Notes

A potent, selective inhibitor of human immunodeficiency virus replication in MT-4 and ATH8 cells

Safety Information

• pictograms: GHS08
• signalword: Warning
• hcodes: H341,H351
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Carc. 2 - Muta. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges