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M86685

Sigma-Aldrich

α-Methyltryptamine

99%

Synonym(s):

3-(2-Aminopropyl)indole

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About This Item

Empirical Formula (Hill Notation):
C11H14N2
CAS Number:
299-26-3
Molecular Weight:
174.24
EC Number:
206-073-7
MDL number:
MFCD00005654
UNSPSC Code:
12352116
PubChem Substance ID:
329818066

Quality Level

100

assay

99%

form

solid

drug control

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada

mp

98-100 °C (lit.)

SMILES string

CC(N)Cc1c[nH]c2ccccc12

InChI

1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3

InChI key

QSQQQURBVYWZKJ-UHFFFAOYSA-N

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
16214TN
09611PF
08227JO
07729HS
07006HO

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S Benkirane et al.
European journal of pharmacology, 131(2-3), 189-198 (1986-11-19)
In slices of the rat hippocampus, alpha 2-adrenoceptors located presynaptically on serotonergic nerve terminals modulate the electrically evoked calcium-dependent release of [3H]serotonin [( 3H]5HT). We have investigated the effects of a naturally occurring trace amine, beta-phenylethylamine (beta-PEA), on noradrenergic transmission
A S Barer et al.
Kosmicheskaia biologiia i aviakosmicheskaia meditsina, 22(6), 66-73 (1988-11-01)
The effect of pharmacological stimulants and prescriptions on the thermal status of man and their possible use to extend the exposure to the cold environment were investigated. The effectiveness of the following drugs and prescriptions was assessed: sydnocarb, phenamine, indopan;
H Scheinin et al.
Pharmacology & toxicology, 61(3), 167-171 (1987-09-01)
The kinetics of monoamine metabolites, 3-methoxy-4-hydroxyphenylglycol (MHPG), 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA), in cisternal CSF were determined after monoamine oxidase (MAO) inhibition (pargyline, 100 mg/kg) and tyrosine hydroxylase inhibition (alpha-methyl-p-tyrosine, alpha-MPT, 250 mg/kg) in awake rats. In addition
Reevaluation of the products of tryptamine catalyzed by rabbit liver N-methyltransferases.
P A Crooks et al.
Biochemical pharmacology, 35(9), 1600-1603 (1986-05-01)
Diane M Boland et al.
Journal of analytical toxicology, 29(5), 394-397 (2005-08-18)
In February 2003, the Miami-Dade County Medical Examiner Department reported the first known death in the country related to alpha-methyltryptamine (AMT). AMT is an indole analogue of amphetamine investigated in the 1960s as an antidepressant, stimulant, and monoamine oxidase inhibitor.
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