545740

(R)-(−)-2-Fluoro-α-methyl-4-biphenylacetic acid

97%

• Synonym(s): (R)-2-Flurbiprofen, Tarenflurbil
• Linear Formula: C₆H₅C₆H₃(F)CH(CH₃)CO₂H
• CAS Number: 51543-40-9
• Molecular Weight: 244.26
• EC Number: 257-264-7
• NACRES: NA.22
• PubChem Substance ID: 24878847
• UNSPSC Code: 12352101
• MDL number: MFCD00869714
• Assay: 97%

Properties

• Quality Segment: 100
• assay: 97%
• mp: 110-113 °C (lit.)
• functional group: fluoro
• SMILES string: C[C@@H](C(O)=O)c1ccc(c(F)c1)-c2ccccc2
• InChI: 1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m1/s1
• InChI key: SYTBZMRGLBWNTM-SNVBAGLBSA-N
• Gene Information: human ... APH1A(51107), APH1B(83464), IL8RA(3577), NCSTN(23385), PSEN1(5663), PSEN2(5664), PSENEN(55851)

Description

Biochem/physiol Actions

gamma secretase inhibitor; amyloid Abeta 42 lowering agent

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301 + H311,H317,H361d
• pcodes: P201 - P202 - P261 - P280 - P301 + P310 - P302 + P352 + P312
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Repr. 2 - Skin Sens. 1B
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges