471836

1-Octanethiol

≥98.5%

• Synonym(s): n-Octyl mercaptan, Mercaptan C₈, Octyl mercaptan
• Linear Formula: CH₃(CH₂)₇SH
• CAS Number: 111-88-6
• Molecular Weight: 146.29
• UNSPSC Code: 12352103
• NACRES: NA.23
• PubChem Substance ID: 24870763
• EC Number: 203-918-1
• Beilstein/REAXYS Number: 1733101
• MDL number: MFCD00004912

Properties

• Quality Segment: 200
• assay: ≥98.5%
• refractive index: n20/D 1.452 (lit.)
• bp: 197-200 °C (lit.)
• density: 0.843 g/mL at 25 °C (lit.)
• SMILES string: CCCCCCCCS
• InChI: 1S/C8H18S/c1-2-3-4-5-6-7-8-9/h9H,2-8H2,1H3
• InChI key: KZCOBXFFBQJQHH-UHFFFAOYSA-N

Description

General description

1-Octanethiol (OT), also known as 1-mercaptooctane, is a high-reactivity linear alkanethiol optimized for the formation of highly ordered Self-Assembled Monolayers (SAMs) on noble metals and semiconductors.
The alkyl chain provides a balance of sufficient hydrophobic shielding to protect underlying circuits from moisture while remaining thin enough to allow for efficient tunneling-based electron transport, a key requirement for molecular electronics.
Due to its low vapor pressure and precise chemical structure, this grade is preferred for cleanroom processes involving vacuum deposition or liquid-phase assembly on micro-electrode arrays. Its ability to create reproducible, uniform molecular layers makes it a standard for fine-tuning surface wetting and adhesion properties in nanofabrication.
Refined to a ≥ 98.5% high-purity specification, this grade ensures the elimination of trace impurities that could lead to lattice defects in the SAM, providing the consistency necessary for high-performance biosensors and nanoelectronic components.

Application

As a versatile linear alkanethiol, 1-Octanethiol is a foundational reagent for creating high-density molecular interfaces in sensing and organic electronic devices.
Nanoelectronic Electrode Engineering: Extensively used to improve charge injection in Thin-Film Transistors (TFTs). By forming a Self-Assembled Monolayer (SAM) on gold source-drain electrodes, it tunes the metal work function and reduces contact resistance, which is critical for bottom-contact device architectures.
Single-Molecule Electronics: Serves as a benchmark molecule for studying electron transport at the nanometer scale. It is utilized to construct single-molecule switches and transistors where conductance can be mechanically or electrically gated.
Precision Biosensing Platforms: Functions as a stabilizing and orienting interphase on gold surfaces for enzyme immobilization (e.g., glucose oxidase). Its hydrophobic chain facilitates the creation of robust "enzyme electrodes" used in point-of-care medical diagnostics.
Quantum Dot & Photovoltaic Enhancement: Acts as a sulfur precursor and ligand for CdSe/CdS quantum dots, improving the power efficiency of nanorod-sensitized solar cells by enhancing electron extraction at the interface.
Nanomaterial Surface Passivation: Used to stabilize copper and gold nanoparticles in colloidal dispersions, preventing oxidation and allowing for their integration into printable conductive inks and optical sensors.

Legal Information

Product of Arkema Inc.

Safety Information

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H317,H335,H410
• pcodes: P261 - P271 - P272 - P273 - P280 - P302 + P352
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk: WGK 3
• flash_point_f: 154.4 °F - closed cup
• flash_point_c: 68 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter