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390593

Sigma-Aldrich

1-(1-Adamantyl)ethylamine hydrochloride

99%

Synonym(s):

α-Methyltricyclo[3.3.1.13,7]-decane-1-methanamine hydrochloride, Rimantadine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C12H21N · HCl
CAS Number:
1501-84-4
Molecular Weight:
215.76
MDL number:
MFCD00072023
UNSPSC Code:
12352100
PubChem Substance ID:
24864331
NACRES:
NA.22

assay

99%

mp

>300 °C (lit.)

SMILES string

Cl.C[C@H](N)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2

InChI

1S/C12H21N.ClH/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12;/h8-11H,2-7,13H2,1H3;1H/t8?,9-,10+,11-,12-;

InChI key

OZBDFBJXRJWNAV-MZHJCFSPSA-N

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pictograms

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GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Georgina Cirrincione-Dall et al.
Journal of clinical pharmacology, 52(8), 1255-1264 (2011-11-01)
Preclinical data suggest increased antiviral activity and less viral resistance when neuraminidase inhibitors and adamantanes are used in combination to harness the complementary effects of their different mechanisms of action. Healthy volunteers were randomized to 5-day oral treatment with oseltamivir
Loren B Andreas et al.
Biochemistry, 52(16), 2774-2782 (2013-03-14)
We demonstrate the use of dynamic nuclear polarization (DNP) to elucidate ligand binding to a membrane protein using dipolar recoupling magic angle spinning (MAS) NMR. In particular, we detect drug binding in the proton transporter M2(18-60) from influenza A using
G G U Rohde
Der Internist, 52(9), 1047-1052 (2011-08-03)
Influenza infections have important socio-economic consequences. Risk groups identified so far include small children and elderly adults with comorbidities. In recent years in addition to seasonal influenza an outbreak of avian influenza occurred in 2005 and the new H1N1 pandemic
V G Belolipetskaia et al.
Eksperimental'naia i klinicheskaia farmakologiia, 74(7), 38-40 (2011-09-08)
Comparative pharmacokinetics of anti-influenza drug composition Antigrippin-maximum administered in capsules and a powder for preparing solutions has been studied after single administraton in a group of 18 healthy volunteers. Both preparations [manufactured by the Antiviral Research and Production Corporation (St
Antiviral drugs for influenza.
The Medical letter on drugs and therapeutics, 54(1381), 1-3 (2012-01-12)
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