335908

Isopropyl chloroformate solution

1.0 M in toluene

• Synonym(s): 1-Methylethyl chloroformate, 2-Propyl chloroformate, Chloroformic acid isopropyl ester, Isopropoxycarbonyl chloride, Isopropyl carbonochloridate, Isopropyl chlorcarbonate, Isopropyl chlorocarbonate
• Linear Formula: (CH₃)₂CHOCOCl
• CAS Number: 108-23-6
• Molecular Weight: 122.55
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 24860351
• MDL number: MFCD00075068
• Beilstein/REAXYS Number: 506416
• Form: liquid

Properties

• form: liquid
• Quality Segment: 100
• concentration: 1.0 M in toluene
• density: 0.892 g/mL at 25 °C
• functional group: chloro
• storage temp.: 2-8°C
• SMILES string: CC(C)OC(Cl)=O
• InChI: 1S/C4H7ClO2/c1-3(2)7-4(5)6/h3H,1-2H3
• InChI key: IVRIRQXJSNCSPQ-UHFFFAOYSA-N

Description

General description

Specific rates of solvolysis of isopropyl chloroformate in various solvents at 25°C has been reported.[1]

Application

Isopropyl chloroform was used in the preparation of isopropyl cyclohexane via alkylation of cyclohexene.[2] It was also used in the preparation of 10-isopropyloctadecanoic acid via reaction with oleic acid in the presence of ethylaluminum sesquichloride[2]

Safety Information

• pictograms: GHS02,GHS06,GHS08,GHS05
• signalword: Danger
• hcodes: H225,H304,H314,H317,H330,H336,H361d,H373,H412
• pcodes: P210 - P280 - P301 + P310 + P331 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 1 Inhalation - Aquatic Chronic 3 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT RE 2 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 3 - Flammable liquids
• flash_point_f: 42.8 °F - closed cup
• flash_point_c: 6 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
• wgk: WGK 2