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335681

Ethylene glycol dimethacrylate

98%, cross-linking reagent polymerization reactions, methacrylate, 90-110 ppm monomethyl ether hydroquinone as inhibitor

Synonym(s):

Polyethylene glycol, 1,2-Ethanediol dimethacrylate, Ethylene dimethacrylate

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Pack SizeSKUAvailabilityPrice
5 mL

Available to ship onMay 20, 2026fromMILWAUKEE

$55.00
100 mL

Available to ship onMay 20, 2026fromMILWAUKEE

$70.50
500 mL

Available to ship onMay 20, 2026fromMILWAUKEE

$185.00

Available to ship onMay 20, 2026fromMILWAUKEE

$690.00

About This Item

Linear Formula:
CH2=C(CH3)COOCH2CH2OCOC(CH3)=CH2
CAS Number:
Molecular Weight:
198.22
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
EC Number:
202-617-2
MDL number:
Beilstein/REAXYS Number:
1776663

$55.00


Available to ship onMay 20, 2026Details


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Product Name

Ethylene glycol dimethacrylate, 98%, contains 90-110 ppm monomethyl ether hydroquinone as inhibitor

vapor density

>1 (vs air)

Quality Segment

vapor pressure

<0.1 mmHg ( 21.1 °C)

assay

98%

form

liquid

contains

90-110 ppm monomethyl ether hydroquinone as inhibitor

reaction suitability

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

refractive index

n20/D 1.454 (lit.)

bp

98-100 °C/5 mmHg (lit.)

density

1.051 g/mL at 25 °C (lit.)

Ω-end

methacrylate

α-end

methacrylate

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

2-8°C

SMILES string

CC(=C)C(=O)OCCOC(=O)C(C)=C

InChI

1S/C10H14O4/c1-7(2)9(11)13-5-6-14-10(12)8(3)4/h1,3,5-6H2,2,4H3

InChI key

STVZJERGLQHEKB-UHFFFAOYSA-N

General description

Ethylene glycol dimethylacrylate (EGDMA) is a diester formed by condensation of two equivalents of methacrylic acid and one equivalent of ethylene glycol.

Application

Ethylene glycol dimethacrylate can be used as a cross-linker in thepreparation of:

  • A terpolymer system, poly(acrylonitrile-co-Ethyleneglycol dimethacrylate-co-vinylbenzyl chloride), which is applicable as a sorbentin pharmaceuticals adsorption.
  • PVA (polyvinyl alcohol) based hydrogel by free-radicalcopolymerization. These PVA polymer networks can be used as drug deliverysystems.
It can also be used asa monomer in the preparation of swellable and non-swellable poly(ethyleneglycol dimethacrylate/acrylic acid) copolymer microspheres through suspensionpolymerization.

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1 of 1

This Item
4090068.18847437468
polymer architecture

shape: linear
functionality: homobifunctional

polymer architecture

shape: linear
functionality: homobifunctional

polymer architecture

-

polymer architecture

shape: linear
functionality: homobifunctional

assay

98%

assay

95%

assay

≥97.5% (GC)

assay

-

form

liquid

form

liquid

form

liquid

form

liquid

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

200

reaction suitability

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

reaction suitability

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

reaction suitability

-

reaction suitability

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

storage temp.

2-8°C

storage temp.

-

storage temp.

2-30°C

storage temp.

2-8°C


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

219.2 °F - Pensky-Martens closed cup

flash_point_c

104 °C - Pensky-Martens closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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Articles

Discover hydrogels, biocompatible materials for drug delivery, tissue engineering, wound care, and 3D bioprinting in innovative biomedical applications

Monomers for ophthalmic use aim for purity, reliability, and comfort, driving innovation for affordable contact lenses.


Robert H Utama et al.
Chemical communications (Cambridge, England), 48(90), 11103-11105 (2012-10-09)
Hollow polymeric nanoparticles with a hydrophilic liquid core have been synthesized in a one-pot approach via a novel inverse miniemulsion periphery RAFT polymerization process. Successful encapsulation and release of a model protein is reported as a potential application.
Andreia F R Pimenta et al.
PloS one, 11(12), e0167728-e0167728 (2016-12-10)
The study of ocular drug delivery systems has been one of the most covered topics in drug delivery research. One potential drug carrier solution is the use of materials that are already commercially available in ophthalmic lenses for the correction
Zhen Wang et al.
Electrophoresis, 33(21), 3151-3158 (2012-09-06)
A microfluidic device that performs "in space" sample fractionation, collection, and preconcentration for proteomics is described. Effluents from a 2.75 mm long fractionation channel, focused via sheath flow, were sequentially delivered into an array of 36-collection channels containing monolithic polymer



Global Trade Item Number

SKUGTIN
335681-500ML04061837887062
335681-100ML04061837887048
335681-4L04065274040028
335681-5ML04061826740200

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Is the ethylene glycol dimethacrylate a toxic crosslinker for human?

    1 answer
    1. The toxicological information for product 335681 can be reviewed in the SDS.
      See the link below, section 13, to review this information:
      https://www.sigmaaldrich.com/sds/aldrich/335681

      There are articles available in the literature as well. See the link to the following publication for an example:
      https://pubmed.ncbi.nlm.nih.gov/29107684/

      Helpful?

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