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For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
269107
L-tert-Leucine
99%, for peptide synthesis
Synonym(s):
(S)-2-Amino-3,3-dimethylbutyric acid, L-α-tert-Butylglycine
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
5 g | Available to ship TODAYfromMILWAUKEE | $129.00 |
25 g | Available to ship TODAYfromMILWAUKEE | $201.00 |
About This Item
$129.00
Available to ship TODAYDetails
Product Name
L-tert-Leucine, 99%
Quality Segment
assay
99%
form
powder
optical activity
[α]20/D −9.5°, c = 3 in H2O
optical purity
ee: 99% (GLC)
reaction suitability
reaction type: solution phase peptide synthesis
mp
≥300 °C (lit.)
application(s)
peptide synthesis
SMILES string
CC(C)(C)[C@H](N)C(O)=O
InChI
1S/C6H13NO2/c1-6(2,3)4(7)5(8)9/h4H,7H2,1-3H3,(H,8,9)/t4-/m1/s1
InChI key
NPDBDJFLKKQMCM-SCSAIBSYSA-N
General description
Application
- As a key precursor in the synthesis of a chiral phosphinooxazoline ligand, (S)-tert-butylPHOX.
- In the synthesis of chiral copper(II) polymers that can catalyze the kinetic resolution of secondary alcohols by acylation.
- In metal-free tandem radical cyclization reactions to synthesize 6-alkyl/acyl phenanthridines.
- In the preparation of tert-leucine-derived N-acetylthiazolidinethione auxiliary that provides high levels of diastereoselection in acetate aldol reactions with a variety of aldehydes.
1 of 1
This Item | |||
|---|---|---|---|
| form powder | form powder | form powder | form powder or crystals |
| assay 99% | assay 98% | assay ≥98% (HPLC) | assay ≥99.5% (NT) |
| mp ≥300 °C (lit.) | mp ≥300 °C (lit.) | mp 280-285 °C (dec.) (lit.) | mp 295-300 °C (subl.) (lit.) |
| optical activity [α]20/D −9.5°, c = 3 in H2O | optical activity [α]25/D +9.5°, c = 3% in H2O | optical activity - | optical activity [α]20/D +27.0±0.5°, c = 5% in 5 M HCl |
| reaction suitability reaction type: solution phase peptide synthesis | reaction suitability reaction type: solution phase peptide synthesis | reaction suitability - | reaction suitability - |
| application(s) peptide synthesis | application(s) peptide synthesis | application(s) cell analysis | application(s) - |
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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