If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
238813
(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid
97%
Synonym(s):
Trolox
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
1 g | Available to ship TODAYfromMILWAUKEE | $87.40 |
5 g | Available to ship TODAYfromMILWAUKEE | $213.00 |
100 g | Available to ship TODAYfromMILWAUKEE | $929.00 |
About This Item
Quality Segment
assay
97%
storage condition
under inert gas
mp
187-189 °C (lit.)
functional group
carboxylic acid
storage temp.
2-8°C
SMILES string
Cc1c(C)c2OC(C)(CCc2c(C)c1O)C(O)=O
InChI
1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)
InChI key
GLEVLJDDWXEYCO-UHFFFAOYSA-N
Gene Information
rat ... Akr1b1(24192)
General description
Application
Packaging
Legal Information
1 of 1
This Item | |||
|---|---|---|---|
| description 97% | description 97% | description A cell-permeable, water-soluble derivative of vitamin E with antioxidant properties. Prevents peroxynitrite-mediated oxidative stress and apoptosis in rat thymocytes. | description 98% |
| assay 97% | assay 97% | assay ≥98% (titration) | assay 98% |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. - | storage temp. 2-8°C | storage temp. - |
| mp 187-189 °C (lit.) | mp ~205 °C (dec.) (lit.) | mp - | mp 162 °C (dec.) (lit.) |
| functional group carboxylic acid | functional group carboxylic acid | functional group - | functional group carboxylic acid |
| storage condition under inert gas | storage condition - | storage condition OK to freeze | storage condition - |
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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How can I determine the shelf life / expiration / retest date of this product?
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for this product, (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox), what is the stability if keep in 4-8 degree. can we keep in-20
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The recommended storage temperature of this product is 2-8°C. The item is not assigned an expiration date, but it periodically retested to assure quality. The assigned retest date is lot specific and may be found in the product Certificate of Analysis. Note that this material is packaged under inert gas. Exposure to air or moisture may accelerate degradation. The stability of this product at freezer temperatures has not been evaluated.
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Bonjour, est-ce que le trolox est soluble dans l'eau svp?
1 answer-
This product has not been tested for solubility in water. Various sources suggest that this material is poorly soluble in water at 0.5 mg/mL. The solubility reportedly increases to 3 mg/mL in PBS at pH 7.2.
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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What is the stability of Trolox in solution? And at what temperature?
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Unfortunately, the solution stability is not determined for this product.
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What is the molar absorption coefficient of Trolox ?
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The molar absorption coefficient is not determined for this product.
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How does the storage temperature relate to shipping conditions?
1 answer-
The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.
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What is the solubility of Product 238813, (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid?
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Product 238813, (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, has been reported to be soluble in DMSO, ethanol and dimethyl formamide. The solubility in these solvents is ~20mg/ml.
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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