143650

5H-Dibenz[b,f]azepine

97%

• Synonym(s): Iminostilbene
• Empirical Formula (Hill Notation): C₁₄H₁₁N
• CAS Number: 256-96-2
• Molecular Weight: 193.24
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 24848600
• EC Number: 205-970-0
• Beilstein/REAXYS Number: 1343358
• MDL number: MFCD00005071
• Assay: 97%

Properties

• Quality Segment: 200
• assay: 97%
• mp: 196-199 °C (lit.)
• solubility: ethyl acetate: soluble 25 mg/mL, clear, yellow to orange
• SMILES string: N1c2ccccc2C=Cc3ccccc13
• InChI: 1S/C14H11N/c1-3-7-13-11(5-1)9-10-12-6-2-4-8-14(12)15-13/h1-10,15H
• InChI key: LCGTWRLJTMHIQZ-UHFFFAOYSA-N

Description

General description

5H-Dibenz[b,f]azepine, a tricyclic amine with a seven-membered ring, is commonly known as iminostilbene. It is used as an intermediate or a starting material in the synthesis of many anticonvulsant drugs.

Application

5H-Dibenz[b,f]azepine can be used:

• As a starting material to prepare pharmacologically important dibenzoazepine-pyridazine derivatives.
• To synthesize 3-chloro-1-(5H-dibenz[b,f]azepine-5yl)propan-1-one, a key intermediate used to prepare aminophenol derivatives.
• In the synthesis of dibenzazepine derivatives.
• As a starting material to synthesize olefinic multidentate ligand, which is used to prepare Rh(I) complexes.

Biochem/physiol Actions

2-(Bromomethyl)naphthalene is a fluorescent alkyl bromide. It causes the esterification of free carboxyl groups formed at the surface of polyethylene terephthalate by enzyme hydrolysis. It acts as organic electrophile in the P₄S₁₀/acyloin reaction.

Safety Information

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H302,H411
• pcodes: P273 - P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves