133892

2,4-Difluorotoluene

99%

• Linear Formula: CH₃C₆H₃F₂
• CAS Number: 452-76-6
• Molecular Weight: 128.12
• NACRES: NA.22
• PubChem Substance ID: 24848122
• UNSPSC Code: 12352100
• EC Number: 207-211-9
• MDL number: MFCD00000332
• Assay: 99%
• Form: liquid

Properties

• assay: 99%
• form: liquid
• refractive index: n20/D 1.449 (lit.)
• bp: 113-117 °C (lit.)
• density: 1.12 g/mL at 25 °C (lit.)
• functional group: fluoro
• SMILES string: Cc1ccc(F)cc1F
• InChI: 1S/C7H6F2/c1-5-2-3-6(8)4-7(5)9/h2-4H,1H3
• InChI key: MPXDAIBTYWGBSL-UHFFFAOYSA-N

Description

General description

2,4-Difluorotoluene was synthesized as a nucleotide analog and was incorporated into DNA and undergoes replication by DNA polymerase enzymes.

Application

2,4-Difluorotoluene was used in the synthesis of new hydrophobic isosteres of pyrimidines and purine nucleosides.

Safety Information

• pictograms: GHS02
• signalword: Danger
• hcodes: H225
• pcodes: P210
• Hazard Classifications: Flam. Liq. 2
• Storage Class: 3 - Flammable liquids
• wgk: WGK 3
• flash_point_f: 59.0 °F - closed cup
• flash_point_c: 15 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter