VAC14
Vac14 homolog (S. cerevisiae)
Synonyms:
ArPIKfyve, TAX1BP2, TRX
Species:
Human VAC14 (55697), Mouse Vac14 (234729), Rat Vac14 (307842), Zebrafish vac14 (447912), domestic guinea pig Vac14 (100726301), naked mole-rat Vac14 (101725753), sheep VAC14 (101114132), domestic cat VAC14 (101093908), Horse VAC14 (100054657), cow VAC14 (533202) ...More
UniProtKB ID:
Gene ID:
- Human(55697) Summary: The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]
- Mouse(234729) Vac14 homolog (S. cerevisiae)
- Rat(307842) Vac14 homolog (S. cerevisiae)
- Zebrafish(447912) vac14 homolog (S. cerevisiae)
- domestic guinea pig(100726301) Vac14 homolog (S. cerevisiae)
- naked mole-rat(101725753) Vac14 homolog (S. cerevisiae)
- sheep(101114132) Vac14 homolog (S. cerevisiae)
- domestic cat(101093908) Vac14 homolog (S. cerevisiae)
- Horse(100054657) Vac14 homolog (S. cerevisiae)
- cow(533202) Vac14 homolog (S. cerevisiae)
- chicken(415678) Vac14 homolog (S. cerevisiae)
- dog(489717) Vac14 homolog (S. cerevisiae)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-VAC14 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-VAC14 antibody produced in mouse, clone 3B2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-VAC14 antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-VAC14 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-VAC14 (C-terminal) antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot