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TLR6

toll-like receptor 6

Synonyms:
CD286
Species:
UniProtKB ID:
Gene ID:
  • Human(10333) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.[provided by RefSeq, Jan 2011]
  • Mouse(21899) toll-like receptor 6
  • Rat(305353) toll-like receptor 6
  • naked mole-rat(101718313) toll-like receptor 6
  • domestic guinea pig(100733137) toll-like receptor 6
  • cow(407237) toll-like receptor 6
  • Horse(100064554) toll-like receptor 6
  • Domestic Rabbit(100353753) toll-like receptor 6
  • dog(100684818) toll-like receptor 6
  • Goat(100860932) toll-like receptor 6
  • domestic cat(493662) toll-like receptor 6
  • sheep(554257) toll-like receptor 6

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TLR6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-TLR6 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-TLR6 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry

western blot
Anti-Mouse Tlr6 (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-TLR6 antibody produced in mouse, clone 4E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TLR6,
Species
human
MISSION® esiRNA, targeting human TLR6 (2),
Species
human
MISSION® esiRNA, targeting mouse Tlr6,
Species
mouse