SRD5A2
steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
Synonyms:
Species:
Human SRD5A2 (6716), Mouse Srd5a2 (94224), Rat Srd5a2 (64677), sheep SRD5A2 (100820756), chicken SRD5A2 (772291), naked mole-rat Srd5a2 (101708836), domestic cat SRD5A2 (101086898), dog SRD5A2 (403715), domestic guinea pig Srd5a2 (100731664), cow SRD5A2 (527024)
UniProtKB ID:
Gene ID:
- Human(6716) Summary: This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008]
- Mouse(94224) steroid 5 alpha-reductase 2
- Rat(64677) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
- sheep(100820756) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
- chicken(772291) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
- naked mole-rat(101708836) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
- domestic cat(101086898) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
- dog(403715) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
- domestic guinea pig(100731664) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
- cow(527024) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SRD5A2 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, rat
Application
ELISA
western blot
western blot
Monoclonal Anti-SRD5A2 antibody produced in mouse, clone 1F4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-SRD5A2, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human
Application
western blot
Anti-SRD5A2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Finasteride for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
esiRNA
Product Number
Description
Species