Skip to Content
MilliporeSigma

SORT1

sortilin 1

Synonyms:
Gp95, LDLCQ6, NT3
Species:
UniProtKB ID:
Gene ID:
  • Human(6272) Summary: This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p; the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins. [provided by RefSeq, Jul 2008]
  • Mouse(20661) sortilin 1
  • Rat(83576) sortilin 1
  • cow(511591) sortilin 1
  • sheep(101104538) sortilin 1
  • domestic guinea pig(100718269) sortilin 1
  • dog(479915) sortilin 1
  • domestic cat(101090199) sortilin 1
  • Horse(100061385) sortilin 1
  • chicken(100858592) sortilin 1
  • naked mole-rat(101698000) sortilin 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
Human Sortilin ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SORT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Sortilin Antibody, serum, Chemicon®,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-SORT1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL6528, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-Sortilin Antibody, clone F11, clone F11, from mouse,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry

immunohistochemistry

western blot
Anti-Sortilin Antibody, clone 4E3.1, clone 4E3.1, from mouse,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Sort1,
Species
mouse
MISSION® esiRNA, targeting human SORT1,
Species
human