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MilliporeSigma

SIRT3

sirtuin 3

Synonyms:
SIR2L3
Species:
Human SIRT3 (23410), Mouse Sirt3 (64384), Rat Sirt3 (293615), cow SIRT3 (614027), Domestic Rabbit SIRT3 (100354500), sheep SIRT3 (101105454), domestic guinea pig Sirt3 (100714713), naked mole-rat Sirt3 (101697494), Zebrafish sirt3 (558775), chicken SIRT3 (422988) ...More
UniProtKB ID:
Q9NTG7, B7Z5U6, Q9Y6E8
Gene ID:
  • Human(23410) Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(64384) sirtuin 3
  • Rat(293615) sirtuin 3
  • cow(614027) sirtuin 3
  • Domestic Rabbit(100354500) sirtuin 3
  • sheep(101105454) sirtuin 3
  • domestic guinea pig(100714713) sirtuin 3
  • naked mole-rat(101697494) sirtuin 3
  • Zebrafish(558775) sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)
  • chicken(422988) sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)
  • domestic cat(101087609) sirtuin 3
  • dog(475933) sirtuin 3

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ELISA

Product Number
Description
Species
RAB1701
Human Sirtuin 3 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
HPA026809
Anti-SIRT3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
AV32388
Anti-SIRT3 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, horse, human, mouse, rat
Application
western blot
S4072
Anti-Sirt3 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
SAB5702277
[KO Validated]Anti-SIRT3 Antibody, clone 7O4G7, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB5700222
Anti-SIRT3 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
SRP5275
SIRT3, active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
SRP0117
Sirtuin 3 human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
EHU093591
MISSION® esiRNA, targeting human SIRT3,
Species
human