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RASSF1

Ras association (RalGDS/AF-6) domain family member 1

Synonyms:
123F2, NORE2A, RASSF1A, RDA32, REH3P21
Species:
UniProtKB ID:
Gene ID:
  • Human(11186) Summary: This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011]
  • Mouse(56289) Ras association (RalGDS/AF-6) domain family member 1
  • Rat(363140) Ras association (RalGDS/AF-6) domain family member 1
  • domestic cat(101094657) Ras association (RalGDS/AF-6) domain family member 1
  • naked mole-rat(101707605) Ras association (RalGDS/AF-6) domain family member 1
  • Zebrafish(447811) Ras association (RalGDS/AF-6) domain family 1
  • chicken(101665483) Ras association (RalGDS/AF-6) domain family member 1
  • chicken(101750777) Ras association (RalGDS/AF-6) domain family member 1
  • dog(607929) Ras association (RalGDS/AF-6) domain family member 1
  • domestic guinea pig(100717305) Ras association (RalGDS/AF-6) domain family member 1
  • cow(510276) Ras association (RalGDS/AF-6) domain family member 1
  • sheep(100302080) Ras association (RalGDS/AF-6) domain family member 1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-RASSF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-RASSF1 Antibody, clone 5C9.1, clone 5C9.1, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-RASSF1, from rabbit, purified by affinity chromatography,
Species Reactivity
human, rat
Application
flow cytometry
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human RASSF1,
Species
human
MISSION® esiRNA, targeting mouse Rassf1,
Species
mouse