PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
Synonyms:
P58, RPN3, S3, TSTA2
Species:
Human PSMD3 (5709), Mouse Psmd3 (22123), Rat Psmd3 (287670), dog PSMD3 (491018), domestic cat PSMD3 (101094305), chicken PSMD3 (426133), Zebrafish psmd3 (393544), domestic guinea pig Psmd3 (100725725), naked mole-rat Psmd3 (101700231), sheep PSMD3 (101105833)
UniProtKB ID:
Gene ID:
- Human(5709) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count. [provided by RefSeq, Jul 2012]
- Mouse(22123) proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
- Rat(287670) proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
- dog(491018) proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
- domestic cat(101094305) proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
- chicken(426133) proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
- Zebrafish(393544) proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
- domestic guinea pig(100725725) proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
- naked mole-rat(101700231) proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
- sheep(101105833) proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
- cow(504937) proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PSMD3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry