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PDZK1

PDZ domain containing 1

Synonyms:
CAP70, CLAMP, NHERF-3, NHERF3, PDZD1
Species:
UniProtKB ID:
Gene ID:
  • Human(5174) Summary: This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
  • Mouse(59020) PDZ domain containing 1
  • Rat(65144) PDZ domain containing 1
  • dog(475823) PDZ domain containing 1
  • Domestic Rabbit(100008900) PDZ domain containing 1
  • Horse(100065636) PDZ domain containing 1
  • chicken(418460) PDZ domain containing 1
  • domestic cat(101096825) PDZ domain containing 1
  • sheep(101116106) PDZ domain containing 1
  • cow(534439) PDZ domain containing 1
  • domestic guinea pig(100729774) PDZ domain containing 1
  • naked mole-rat(101696284) PDZ domain containing 1
  • Zebrafish(337325) PDZ domain containing 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PDZK1 Antibody, clone 5C1D3, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
Anti-PDZK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-PDZK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PDZK1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PDZK1,
Species
human
MISSION® esiRNA, targeting mouse Pdzk1,
Species
mouse