OAZ3
ornithine decarboxylase antizyme 3
Synonyms:
AZ3, OAZ-t, TISP15
Species:
Human OAZ3 (51686), Mouse Oaz3 (53814), Rat Oaz3 (689588), domestic guinea pig Oaz3 (100726348), naked mole-rat Oaz3 (101699127), cow OAZ3 (531865), dog OAZ3 (475850), Horse OAZ3 (100055594), sheep OAZ3 (101119005), domestic cat OAZ3 (101081153)
UniProtKB ID:
Gene ID:
- Human(51686) Summary: Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of this gene product (antizyme 3) is restricted to testis germ cells, and thus it is a possible candidate for heritable forms of human male infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
- Mouse(53814) ornithine decarboxylase antizyme 3
- Rat(689588) ornithine decarboxylase antizyme 3
- domestic guinea pig(100726348) ornithine decarboxylase antizyme 3
- naked mole-rat(101699127) ornithine decarboxylase antizyme 3
- cow(531865) ornithine decarboxylase antizyme 3
- dog(475850) ornithine decarboxylase antizyme 3
- Horse(100055594) ornithine decarboxylase antizyme 3
- sheep(101119005) ornithine decarboxylase antizyme 3
- domestic cat(101081153) ornithine decarboxylase antizyme 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-OAZ3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence