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NDUFS7

NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)

Synonyms:
CI-20, CI-20KD, MY017, PSST
Species:
UniProtKB ID:
Gene ID:
  • Human(374291) Summary: This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions. [provided by RefSeq, Jul 2008]
  • Mouse(75406) NADH dehydrogenase (ubiquinone) Fe-S protein 7
  • Rat(362837) NADH dehydrogenase (ubiquinone) Fe-S protein 7
  • domestic cat(101096448) NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
  • Zebrafish(796997) NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)
  • chicken(770724) NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
  • domestic guinea pig(100731963) NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
  • dog(476754) NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
  • cow(338079) NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
  • sheep(101114702) NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
  • Goat(100860782) NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
  • naked mole-rat(101702397) NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NDUFS7 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
Monoclonal Anti-NDUFS7, (C-terminal) antibody produced in mouse, clone 3A3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA

Small Molecule - Inhibitor

Product Number
Description
Species
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
1,1-Dimethylbiguanide hydrochloride, 97%,
Species
human
Metformin hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Metformin hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human NDUFS7,
Species
human
MISSION® esiRNA, targeting mouse Ndufs7,
Species
mouse