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MRPS18A

mitochondrial ribosomal protein S18A

Synonyms:
HumanS18b, MRP-S18-3, MRPS18-3, S18bmt
Species:
UniProtKB ID:
Gene ID:
  • Human(55168) Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. A pseudogene corresponding to this gene is found on chromosome 3p. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]
  • Mouse(68565) mitochondrial ribosomal protein S18A
  • Rat(301249) mitochondrial ribosomal protein S18A
  • dog(474917) mitochondrial ribosomal protein S18A
  • domestic guinea pig(100731034) mitochondrial ribosomal protein S18A
  • domestic cat(101089692) mitochondrial ribosomal protein S18A
  • sheep(101116355) mitochondrial ribosomal protein S18A
  • cow(614102) mitochondrial ribosomal protein S18A
  • naked mole-rat(101707091) mitochondrial ribosomal protein S18A
  • Zebrafish(558080) mitochondrial ribosomal protein S18A
  • chicken(421445) mitochondrial ribosomal protein S18A
  • fruit fly(326141) mitochondrial ribosomal protein S18A

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MRPS18A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-MRPS18A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MRPS18A,
Species
human
MISSION® esiRNA, targeting mouse Mrps18a,
Species
mouse