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MRPL43

mitochondrial ribosomal protein L43

Synonyms:
bMRP36a
Species:
UniProtKB ID:
Gene ID:
  • Human(84545) Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(94067) mitochondrial ribosomal protein L43
  • Rat(309440) mitochondrial ribosomal protein L43
  • domestic cat(101093715) mitochondrial ribosomal protein L43
  • cow(282277) mitochondrial ribosomal protein L43
  • naked mole-rat(101719220) mitochondrial ribosomal protein L43
  • domestic guinea pig(100734372) mitochondrial ribosomal protein L43
  • Zebrafish(436701) mitochondrial ribosomal protein L43
  • fruit fly(37750) mitochondrial ribosomal protein L43
  • dog(477799) mitochondrial ribosomal protein L43
  • sheep(101122995) mitochondrial ribosomal protein L43

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MRPL43 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Mrpl43,
Species
mouse
MISSION® esiRNA, targeting human MRPL43,
Species
human