KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
Synonyms:
KCa2.2, SK2, SKCA2, SKCa 2, hSK2
Species:
Human KCNN2 (3781), Mouse Kcnn2 (140492), Rat Kcnn2 (54262), naked mole-rat Kcnn2 (101725711), domestic guinea pig Kcnn2 (100734732), sheep KCNN2 (101105660), domestic cat KCNN2 (101099926), cow KCNN2 (404177), dog KCNN2 (474640), chicken KCNN2 (395579)
UniProtKB ID:
Gene ID:
- Human(3781) Summary: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
- Mouse(140492) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
- Rat(54262) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
- naked mole-rat(101725711) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
- domestic guinea pig(100734732) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
- sheep(101105660) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
- domestic cat(101099926) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
- cow(404177) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
- dog(474640) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
- chicken(395579) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-KCNN2 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human, yeast
Application
immunohistochemistry
western blot
western blot
Anti-KCNN2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-Potassium Channel SK2 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
human, rat
Application
western blot
Anti-SK2 (KCa2.2) Antibody, clone K78/29, clone K78/29, from mouse,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot