IKZF3
IKAROS family zinc finger 3 (Aiolos)
Synonyms:
AIO, AIOLOS, ZNFN1A3
Species:
Human IKZF3 (22806), Mouse Ikzf3 (22780), Rat Ikzf3 (303511), domestic cat IKZF3 (101092807), chicken IKZF3 (395614), dog IKZF3 (491020), sheep IKZF3 (101104255), cow IKZF3 (540676), naked mole-rat Ikzf3 (101703429), domestic guinea pig Ikzf3 (100727931)
UniProtKB ID:
Gene ID:
- Human(22806) Summary: This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]
- Mouse(22780) IKAROS family zinc finger 3
- Rat(303511) IKAROS family zinc finger 3
- domestic cat(101092807) IKAROS family zinc finger 3 (Aiolos)
- chicken(395614) IKAROS family zinc finger 3 (Aiolos)
- dog(491020) IKAROS family zinc finger 3 (Aiolos)
- sheep(101104255) IKAROS family zinc finger 3 (Aiolos)
- cow(540676) IKAROS family zinc finger 3 (Aiolos)
- naked mole-rat(101703429) IKAROS family zinc finger 3 (Aiolos)
- domestic guinea pig(100727931) IKAROS family zinc finger 3 (Aiolos)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Aiolos Antibody, clone 9D10, clone 9D10, from mouse,
Species Reactivity
human, mouse
Application
ChIP
western blot
western blot
Anti-IKFZ3 degron tag Antibody, clone 1C3-D3-F8, ,
Species Reactivity
bovine, human, monkey, rat
Application
western blot
Anti-IKZF3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-IKZF3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-IKZF3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry