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GEMIN2

gem (nuclear organelle) associated protein 2

Synonyms:
SIP1, SIP1-delta
Species:
UniProtKB ID:
Gene ID:
  • Human(8487) Summary: This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011]
  • Mouse(66603) gem (nuclear organelle) associated protein 2
  • Rat(84404) gem (nuclear organelle) associated protein 2
  • domestic cat(101083009) gem (nuclear organelle) associated protein 2
  • domestic guinea pig(100732674) gem (nuclear organelle) associated protein 2
  • naked mole-rat(101715665) gem (nuclear organelle) associated protein 2
  • sheep(101122894) gem (nuclear organelle) associated protein 2
  • dog(610087) gem (nuclear organelle) associated protein 2
  • Zebrafish(550271) gem (nuclear organelle) associated protein 2
  • chicken(423336) gem (nuclear organelle) associated protein 2
  • cow(510259) gem (nuclear organelle) associated protein 2

Custom & Knockdown Gene Products

  • siRNA

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Gemin2 Antibody, clone 2E17, clone 2E17, from mouse,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry

immunoprecipitation (IP)

western blot
Anti-GEMIN2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-GEMIN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-GEMIN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GEMIN2,
Species
human