GCSH
glycine cleavage system protein H (aminomethyl carrier)
Synonyms:
GCE, NKH
Species:
Human GCSH (2653), Mouse Gcsh (68133), Rat Gcsh (171133), cow GCSH (317723), sheep GCSH (101120772), Domestic Rabbit GCSH (100009476), dog GCSH (479633), chicken GCSH (415803), domestic cat GCSH (101084333), domestic guinea pig Gcsh (100721850)
UniProtKB ID:
Gene ID:
- Human(2653) Summary: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.[provided by RefSeq, Jan 2010]
- Mouse(68133) glycine cleavage system protein H (aminomethyl carrier)
- Rat(171133) glycine cleavage system protein H (aminomethyl carrier)
- cow(317723) glycine cleavage system protein H (aminomethyl carrier)
- sheep(101120772) glycine cleavage system protein H (aminomethyl carrier)
- Domestic Rabbit(100009476) glycine cleavage system protein H (aminomethyl carrier)
- dog(479633) glycine cleavage system H protein, mitochondrial-like
- chicken(415803) glycine cleavage system protein H (aminomethyl carrier)
- domestic cat(101084333) glycine cleavage system protein H (aminomethyl carrier)
- domestic guinea pig(100721850) glycine cleavage system protein H (aminomethyl carrier)
- naked mole-rat(101724619) glycine cleavage system protein H (aminomethyl carrier)
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GCSH antibody produced in mouse, clone 3D8-A12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-GCSH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-GCSH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot