DEFA4
defensin, alpha 4, corticostatin
Synonyms:
DEF4, HNP-4, HP-4, HP4
Species:
UniProtKB ID:
Gene ID:
- Human(1669) Summary: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq, Jul 2008]
- Mouse(13238) defensin, alpha, 4
- Horse(100307026) defensin, alpha 4, corticostatin
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DEFA4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
esiRNA
Product Number
Description
Species