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DCTN3

dynactin 3 (p22)

Synonyms:
DCTN-22, DCTN22
Species:
UniProtKB ID:
Gene ID:
  • Human(11258) Summary: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
  • Mouse(53598) dynactin 3
  • Rat(362504) dynactin 3
  • sheep(101121236) dynactin 3 (p22)
  • domestic guinea pig(100726120) dynactin 3 (p22)
  • naked mole-rat(101706314) dynactin 3 (p22)
  • Zebrafish(431767) dynactin 3 (p22)
  • chicken(427404) dynactin 3 (p22)
  • dog(474750) dynactin 3 (p22)
  • domestic cat(101083978) dynactin 3 (p22)
  • cow(514327) dynactin 3 (p22)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-DCTN3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, rabbit, rat
Application
western blot
Anti-DCTN3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, mouse, rat
Application
ELISA
flow cytometry

immunohistochemistry

western blot
Anti-DCTN3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Dctn3,
Species
mouse
MISSION® esiRNA, targeting human DCTN3,
Species
human