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COPS8

COP9 signalosome subunit 8

Synonyms:
COP9, CSN8, SGN8
Species:
UniProtKB ID:
Gene ID:
  • Human(10920) Summary: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(108679) COP9 (constitutive photomorphogenic) homolog, subunit 8 (Arabidopsis thaliana)
  • Rat(363283) COP9 signalosome subunit 8
  • domestic cat(101081071) COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
  • Zebrafish(393198) COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
  • chicken(424020) COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
  • domestic guinea pig(100729283) COP9 signalosome subunit 8
  • naked mole-rat(101716724) COP9 signalosome subunit 8
  • cow(540493) COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
  • sheep(101102596) COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
  • dog(477417) COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-COPS8 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-COPS8 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-COPS8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-COPS8 antibody produced in mouse, clone 2G8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-CSN8 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human COPS8,
Species
human
MISSION® esiRNA, targeting mouse Cops8,
Species
mouse