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MilliporeSigma

CHMP2A

charged multivesicular body protein 2A

Synonyms:
BC-2, BC2, CHMP2, VPS2, VPS2A
Species:
UniProtKB ID:
Gene ID:
  • Human(27243) Summary: CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]
  • Mouse(68953) charged multivesicular body protein 2A
  • Rat(365191) charged multivesicular body protein 2A
  • chicken(776036) charged multivesicular body protein 2A
  • domestic guinea pig(100717259) charged multivesicular body protein 2A
  • naked mole-rat(101722413) charged multivesicular body protein 2A
  • sheep(101112505) charged multivesicular body protein 2A
  • cow(523847) charged multivesicular body protein 2A
  • domestic cat(101085934) charged multivesicular body protein 2A
  • dog(476364) charged multivesicular body protein 2A

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CHMP2A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, guinea pig, human, mouse, rabbit, rat
Application
western blot
Anti-CHMP2A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-CHMP2A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CHMP2A,
Species
human