CDK11A
cyclin-dependent kinase 11A
Synonyms:
CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, PITSLRE, p58GTA
Species:
Human CDK11A (728642), Horse CDK11A (100033941), dog CDK11A (489591), naked mole-rat Cdk11a (101714919)
UniProtKB ID:
Gene ID:
- Human(728642) Summary: This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L1, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L1, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions, which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L1 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Many transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of only two have been determined so far. [provided by RefSeq, Jul 2008]
- Horse(100033941) cyclin-dependent kinase 11A
- dog(489591) cyclin-dependent kinase 11A
- naked mole-rat(101714919) cyclin-dependent kinase 11A
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CDK11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-CDK11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-CDK11A/CDK11B antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot