C4BPB
complement component 4 binding protein, beta
Synonyms:
C4BP
Species:
Human C4BPB (725), Rat C4bpb (24236), cow C4BPB (281652), domestic guinea pig C4bpb (100713956), dog C4BPB (609285), sheep C4BPB (101114204), naked mole-rat C4bpb (101720955), domestic cat C4BPB (101095148)
UniProtKB ID:
Gene ID:
- Human(725) Summary: This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008]
- Rat(24236) complement component 4 binding protein, beta
- cow(281652) complement component 4 binding protein, beta
- domestic guinea pig(100713956) complement component 4 binding protein, beta
- dog(609285) complement component 4 binding protein, beta
- sheep(101114204) complement component 4 binding protein, beta
- naked mole-rat(101720955) complement component 4 binding protein, beta
- domestic cat(101095148) complement component 4 binding protein, beta
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-C4BPB antibody produced in mouse, clone 1G9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-C4BPB antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-C4BPB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-C4BPB antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-C4BPB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
esiRNA
Product Number
Description
Species