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B4GALT3

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3

Synonyms:
beta4Gal-T3
Species:
UniProtKB ID:
Gene ID:
  • Human(8703) Summary: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]
  • Mouse(57370) UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3
  • Rat(494342) UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3
  • chicken(418342) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
  • dog(488650) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
  • domestic cat(101089738) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
  • cow(515771) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
  • naked mole-rat(101702700) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
  • sheep(101103686) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
  • Domestic Rabbit(100358436) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
  • domestic guinea pig(100712729) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-B4GALT3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot
Anti-B4GALT3 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human B4GALT3,
Species
human
MISSION® esiRNA, targeting mouse B4galt3,
Species
mouse