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ARID1A

AT rich interactive domain 1A (SWI-like)

Synonyms:
B120, BAF250, BAF250a, BM029, C1orf4, ELD, MRD14, OSA1, P270, SMARCF1, hELD, hOSA1
Species:
UniProtKB ID:
Gene ID:
  • Human(8289) Summary: This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(93760) AT rich interactive domain 1A (SWI-like)
  • Rat(297867) AT rich interactive domain 1A (SWI-like)
  • sheep(101115263) AT rich interactive domain 1A (SWI-like)
  • cow(540181) AT rich interactive domain 1A (SWI-like)
  • domestic cat(101086737) AT rich interactive domain 1A (SWI-like)
  • naked mole-rat(101715459) AT rich interactive domain 1A (SWI-like)
  • dog(487352) AT rich interactive domain 1A (SWI-like)
  • domestic guinea pig(100714305) AT rich interactive domain 1A (SWI-like)
  • chicken(419542) AT rich interactive domain 1A (SWI-like)

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ARID1A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot
Anti-ARID1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-BAF250a/ARID1a Antibody, clone PSG3, clone PSG3, Upstate®, from mouse,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-ARID1A Antibody, clone 1C3 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, human, monkey, mouse, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-ARID1A Antibody, clone 9D4J6, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Arid1a,
Species
mouse
MISSION® esiRNA, targeting human ARID1A,
Species
human